A milligram of gluten a day keeps the mucosal recovery away: A case report

Federico Biagi, Jonia Campanella, Susi Martucci, Donatella Pezzimenti, Paul J. Ciclitira, Heather J. Ellis, Gino R. Corazza

Research output: Contribution to journalArticlepeer-review


In recent years it has been suggested that patients with celiac disease can be adequately followed up on the basis of merely clinical and serological response to a gluten-free diet. Thus, a duodenal biopsy some months after commencement of a gluten-free diet would no longer be necessary. We report here the case of a celiac patient in whom the ingestion of a milligram of gluten every day for 2 years prevented histological recovery in spite of satisfactory clinical and serological response. The literature regarding the minimal amount of gluten that could be harmless to celiac patients is reviewed.

Original languageEnglish
Pages (from-to)360-363
Number of pages4
JournalNutrition Reviews
Issue number9
Publication statusPublished - Sept 2004


  • Celiac disease
  • Endomysial antibody
  • Gliadin
  • Gluten-free diet
  • Villous atrophy

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science


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